大鼠脑、垂体和肾上腺内5-羟色胺及去甲肾上腺素神经元和纤维的分布

Distribution of 5 HT and NE Nerve Cells and Fibre in Rat′s Brain

给药组大鼠腹腔注射优降宁、Ｌ色氨酸等促进５ＨＴ合成并抑制其降解的药物；对照组不经任何处理。用免疫组化方法染色观察５ＨＴ及ＮＥ神经元在脑内的分布及其神经纤维在垂体及肾上腺内的分布。结果表明，５ＨＴ神经元在不给药组中只出现在脑干，给药后，在丘脑下部亦可染出；ＮＥ神经元在膈区、丘脑下部、脑干等处均可染出；垂体中间叶、神经垂体有５ＨＴ及ＮＥ神经纤维分布；肾上腺内可见大量５ＨＴ及ＮＥ阳性细胞。

Adult female rats were used and divided into two groups. The experimental rats were injec ted abdominally with pargiline and L tryptophan which can promote the synthesis of 5HT, while inhibit the disintegration of it. The normal control rats were treated with nothing. The immunohistochemistry method was used to observe the distribution of 5HT nerve cells in brain and the fibres in pituitary and adrenal. It was found that the 5HT nerve cells can only be found in brainstem in the normal control group, while it can also be found in hypothalamus in the experimental group. The NE nerve cells were distributed in septal area, hypothalamus and brainstem. In pituitany intermediate lobe and neuroal lobe, can be found the fibres of 5HT and NE. Lots of 5HT and NE cell can be found in adrenal.