肥胖儿童脂代谢变化及其与身体指标的相关性研究

A Study on Relationship between Body Status and Metabolism of Lipids in Simple Obese Children

检测１０２例６～１５岁单纯肥胖症儿童及７７例同龄健康儿童的血脂及身体指标，以探讨肥胖儿童脂质代谢的变化及其与Ｒｏｈｌｅｒ指数、体质量（体重）指数（ＢＭＩ）的相关关系。发现肥胖儿童较健康儿童胆固醇（ＴＣ）、甘油三酯（ＴＧ）、极低密度脂蛋白胆固醇（ＶＬＤＬＣ）及低密度脂蛋白胆固醇（ＬＤＬＣ）、动脉硬化指数（ＡＩ）明显增高（Ｐ＜０．００１、０．０１及０．０５），高密度脂蛋白胆固醇（ＨＤＬＣ）及其与ＴＣ之比值明显降低（Ｐ＜０．０５及０．００１）。多元逐步回归证实，在排除众多血脂因素之后，肥胖儿童ＴＧ分别与Ｒｏｈｌｅｒ指数及ＢＭＩ呈明显正相关，是影响Ｒｏｈｌｅｒ指数与ＢＭＩ的独立因素。

For investigation of the correlation between body status and metabolism of lipids, the lipid levels and body mass index, Rohler index were examined in 102 simple obese children aged 6 to 15 years and 77 age matched healthy children. It was found that total cholesterol, triglyceride, very low density lipoprotein, low density lipoprotein cholesterol and atherosclerosis index were significantly increased( P <0.05, and P <0.01), while the level of high density lipoprotein was decreased( P <0.05), in obese children than in healthy children. Stepwise multivaritate regression analysis disclosed that triglyceride alone and jointly positively correlated with body mass index and Rohler index except multiple markers of lipids.