摘要
目的研究肺癌患者围术期换气功能的改变规律及影响机制。方法用氧合指数(P/F)、动脉肺泡氧分压比(a/A)、动脉血氧饱和度50%的氧分压(P50O2)、动脉血二氧化碳分压(PaCO2)4项指标对68例50岁以上男性肺癌患者分别于术前、术后即日、1、2、3、7日围术期换气功能进行监测。结果肺癌术后3日内P/F、a/A较术前显著降低(P<0.01);PaCO2、P50O2术后即日较术前显著增加(P<0.01);术后2日内全肺切除氧合功能降低大于肺叶切除(P<0.05);低肺功能患者术后换气及通气功能障碍较肺功能正常者显著(P<0.05)。结论肺癌术后3日换气功能明显减退,尤以氧合功能降低显著。应重点监测氧合功能变化,加强全肺及低肺功能患者的换气功能监测。
Objective To study changes of gas exchange in perioperative patients with lung cancer. Method Indices including P/F,a/A, P 50 O 2 and PaCO 2 on gas exchange in 68 male patients(50 78y) with lung caner were monitored on preoperative day 1 2 3 and postopertive day 7. Result Comparing with preoperation data P/F a/A decreased significantly in 3 days( P <0.01) and PaCO 2 P 50 O 2 incresesd significantly on the day after operation ( P <0.01), especially in the group of pneumonectomy and abnormal ventilation,hypoxemia measured in preoperation. Conclusion The gas exchange of the patients with lung caner reduced significantly in postoperative 3 days.
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
1998年第12期735-738,共4页
Chinese Journal of Tuberculosis and Respiratory Diseases