1Grines C L, Bonow R O, Casey D E, et al. Prevention of premature discontinuation of dual antiplatelet therapy in Aatients with coronary artery stents:a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, with representation from the American College of Physicians [J]. Circulation,2007,115 ( 6 ) : 813- 818.
2Hallas J, Dall M, Andries A, et al. Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding : population based case-control study [J]. BMJ, 2006, 333:726-730.
3Foley P,Foley S,Kinnaird T,et al. Clinical review:gastrointestinal bleeding after percutaneous coronary intervention: a deadly combination[ J ]. Q J Med ,2008, 101 (6) :425-433.
4Patrono C, Bachmann F, Baigent C, et al. Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European Society of Cardiology [J]. Eur Heart J,2004,25(2) :166-181.
5Lai K C, Lam S K, Chu K M, et al. Lansoprazole for the prevention of recurrences of ulcer complications from long-term lowdose aspirin use [ J ]. N Engl J Med, 2002, 346 ( 26 ) : 2033-2038.
6CAPRIE Investigators. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee [J]. Lancet, 1996, 348 (9038): 1329-1339.
7Eikelboom J W, Hirsh J. Bleeding and management of bleeding [J]. Eur Heart J,2006,8 ( Suppl G) : G38-45.
8Ng F H, Wong S Y, Chang C M, et al. High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease [ J ]. Aliment Pharmacol Ther, 2003,18(4) :443-449.
9Yusuf S, Zhao F, Mehta S R, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation [J]. N Engl J Med, 2001,345: 494-502.
10Joseph A D, Lucie O, James M B,et al. Drug-drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding[J]. CMAJ,2007,177 (4) :347-351.
3Bhatt DI., Scheiman J, Abraham NS. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of theAmerican College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents[J]. Circulation, 2008,52 (18) :1502-1517.
5Vallurupalli NG, Goldhaber SZ. Gastrointestinal complications of dual antiplatelet therapy [J]. Circulation, 2006, 113 ( 12 ) e655-e658.
6Bassand JP, Hamm CW, Ardissino D,et al. Guidelines for the diagnosis and treatment of non-ST-segmentelevation acute coronary syndromes[J]. Rev Port Cardiol, 2008,27 ( 9 ) : 1063-1143.
7Barkun AN, Bardou M, Kuipers EJ, et al. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding [J]. AnnIntern Med,2010,152(2):l0l-l13.
8Siriswangvat S, Sansanayudh N, Nathisuwan S, et al. Comparison between the effect of omeprazole and rabeprazole on the antiplatelet action of clopidogrel[J]. Circ J, 2010, 74 (10) : 2187-2192.
9Stoekl KM, Le L, Zakharyan A, et al. Risk of rehospitalization for patients using clopidogrel with a protonpump inhibitor[J]. Arch Intern Med, 2010,170 (8) : 704-710.
10Yasuda H, Yamada M, Sawada S,et al. Upper gastrointestinal bleeding in patients receiving dual antiplatelet therapy after coronary stenting[J]. Inter Med, 2009,48(19) : 1725-1730.