摘要
弥漫性大B细胞淋巴瘤(DLBCL)是一组B淋巴细胞来源最常见的、且具有异质性的非霍奇金淋巴瘤(NHL)。就DLBCL中t(14;18)易位和c—myc基因重排及其诊断分型、治疗和预后评价方面的最新研究进展进行综述。
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of tumors composed of large B cells. It is the most common type of non-Hodgkin lymphoma. As its variety of clinical, morphological and genetic characters, the classification and prognosis are still debated. This article aims to elucidate t(14;18) translocation and c-myc gene rearrangement is of great significance to the clinical diagnosis, classification, treatment and prognosis of DLBCL.
出处
《白血病.淋巴瘤》
CAS
2009年第10期630-633,共4页
Journal of Leukemia & Lymphoma
关键词
淋巴瘤
非霍奇金
淋巴瘤
弥漫型
基因重排
研究
Lymphoma, non-Hodgkin
Lymphoma, diffuse
Rearrangement, gene
Research