氧代-β-紫罗兰酮的合成

Synthesis of Oxo-β-ionone

在吡啶溴鎓和吡啶氯鎓离子液[Epy]Br、[Bpy]Br和[Bpy]Cl中,以氯化亚铜为催化剂,叔丁基过氧化氢为氧化剂,可以直接将β-紫罗兰酮选择性氧化合成4-氧代-β-紫罗兰酮,收率可达55%。该方法使用了无毒的氧化剂和催化剂,反应介质和催化剂氯化亚铜可回收再利用,因此是一种有效和环境友好的合成氧代-β-紫罗兰酮的方法。

Using copper（I） chloride as catalyst and tert butyl hydroperoxide as oxidant,β-ionone could be selectively oxidized to 4 oxo-β-ionone with yield of 55 % in ethyl or butyl pyridinium bromide or chloride ionic liquids, [Epy]Br, [Bpy]Br and[Bpy]Cl. This is an efficient ancl green procedure because of the utilization of less toxic oxidant and copper salt catalyst, and the recovery and reuse of the catalytic system have been achieved.