医疗费用效果分析中的检验方法及其应用

Statistical Methods for Treatment Cost-effectiveness and its Application

目的：借用生存分析的方法，将“医疗费用”视为生存分析中的“生存时间”，“治愈和未治愈”视为生存分析中的“死亡和仍活着”，探讨该考察指标的统计检验问题。方法：给出了每治愈一例，两种治疗方案的平均费用的显著性检验方法（指数分布均数检验法）以及数据应满足的条件，进一步介绍了用非参数检验方法ｌｏｇｒａｎｋ进行分析和检验。结果：对每治愈一例，两组平均费用进行显著性差异检验。发现两种检验方法的结果接近，结论相同。结论：治愈一例患者的平均费用的显著性检验可以采用指数分布均数检验法进行分析，但要求资料近似服从指数分布；

Objective:The survival analysis methods would be used to test this index with the treatment cost corresponding to the survival time,patient cured corresponding to patient died,and patient uncured corresponding to patient alive in survival analysis.Therefore the statistical test of this index would be explored in this paper.Methods:This paper showed two statistical methods:exponential mean test with its assumptions and logrank to test the main index of the cost effectiveness for two treatments.Results:For the cost effectiveness of two treatments for Helicobacter Pylori-related duodenal ulcer,the results from the two test methods are similar and the conclusions in this numeral example are the same for the two methods .Conclusion:the exponential mean test method can be used to test the average cost of the treatment curing one patient statistically when the data follows approximately an exponential distribution;nonparametric test logrank can also be used to analyze and test the expected treatment cost curing one patient statistically.