正常孕妇不同孕期心律失常及心率变异分析

Analysis of arrhythmia and heart rate variability in different pregnancy duration of normal pregnant women

目的探讨正常孕妇心律失常发生率及心脏自主神经功能的平衡改变情况。方法对300例正常孕妇(按妊娠周期分成3组)和100例正常未孕妇女进行Holter检查,监测24 h心率、心律及心律失常发生情况,分析24 h心率变异,对其时域、频域结果进行分析。结果怀孕各组各类心律失常发生率均高于对照组(P均<0.05)。与对照组相比,怀孕各组心率变异各常用时域、频域分析指标均明显降低(P均<0.05)。结论健康在孕期心律失常发生率高,且心率变异值降低,可能与心脏自主神经功能失衡有关。对不同阶段孕期妇女行Holter监测对评价孕期可能存在潜在心脏疾病危险具有一定的临床意义。

Objective It is to approach the incidence rate of arrhythmia and the equilibrium altering status of cardiac autonomic nervous function in normal pregnant women. Methods 300 cases of normal pregnant women who were divided into three groups according to gestation period and 100 cases of normal nonfertile women were examined with Holter. 24 h heart rate, cardiac rhythm and incidence status of arrhythmia were monitored. 24 h heart rate variability was analyzed. The time domain and frequency domain were analyzed. Results The incidence rates of various kinds arrhythmia in pregnant groups were all higher than those in control group （all P〈0.05）. Compared with control group, the analysis indexes of time domain and frequency domain of heart rate variability in pregnant groups were all obviously lowered （all P 〈 0.05）. Conclusion The incidence rate of arrhythmia is high and heart rate variability lowers in normal pregnant women, which maybe related with cardiac autonomic nervous function disbalance. Holter monitoring on pregnant women in different gestation period has determinate clinical significance for appraising potential hazard of heart disease in gestation period.