慢性前列腺炎/慢性骨盆疼痛综合征的相关危险因素分析

Analysis of the correlated risk factors of chronic prostatitis/chronic pelvic pain syndrome

目的探讨慢性前列腺炎/慢性骨盆疼痛综合征(CP/CPPS)发病的危险因素。方法选择360例临床确诊的CP/CPPS患者及年龄匹配的非CP/CPPS患者360例(对照组),采用自行设计调查表进行病例对照研究,内容主要包括吸烟及饮酒情况、受教育程度、居住地、婚姻状况,采用非条件多元Logistic回归模型测量各因素与CP/CPPS发病的相关性。结果与不吸烟者比较,吸烟者发生CP/CPPS的危险性升高,吸烟量和吸烟时间均与CP/CPPS发病率呈明显正相关;与不饮酒者相比,饮酒者发生CP/CPPS的危险性降低,随饮酒量和时间增长,CP/CPPS发病危险有下降趋势;CP/CPPS发病危险性受教育程度为初中以下者高于初中以上者,居住农村者高于居住城区者,已婚者高于未婚者。结论吸烟是CP/CPPS发病的危险因素,饮酒为保护性因素,文化程度低、居住条件差及已婚等因素可增加CP/CPPS发病的危险性。

Objective To investigate the pathogenetie risk factors of chronic prostatitis/chronic pelvic pain syndrome （CP/CPPS）. Methods Total 360 cases of clinically diagnosed CP/CPPS and 360 age-matched pateients with non-CP/ CPPS（eontrol group） were investigated,then the case-control study were performed by using the self-designed questionnaire, which included smoking, drinking, educational background, place of residence and marriage status, the correlations between related variables and pathogenesis of CP/CPPS were measured by unconditional multiple logistic regression models. Results Compared with the non-smokers, the CP/CPPS risk of the smokers increased , and the amount and time of smok- ing were positively correlated with the incidence rate of CP/CPPS. Compared with the non-drinkers, the CP/CPPS risk of the drinkers decreased, and the morbidity showed downtrend with the quantity and time of drinking. The morbidity of CP/ CPPS in cases whose educational background lower than Middle School were higher than that in cases with higher educational background, the difference were also found between the cases in rural and city , the cases married and unmarried. Conclusions Smoking is a risk factor for CP/CPPS,while drinking is the protective factor,low level of education, poor living conditions and marriage may increase the the morbidity risk of CP/CPPS.