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幽门螺杆菌感染与食管癌关系探讨 被引量:9

Correlation Between Helicobacter Pylori Infection and Esophageal Cancer
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摘要 为了解人群中食管幽门螺杆菌的感染情况及其与食管癌的关系,作者对43例食管癌病人和170例正常人的食管、胃窦部和十二指肠球部的纤支镜活检组织进行幽门螺杆菌快速尿素酶试验,并对食管癌组织中的幽门螺杆菌形态及致病性进行电镜观察。结果发现,正常人群中食管幽门螺杆菌的感染率为25.3%,食管癌病人的感染率为90.7%;受幽门螺杆菌感染的食管上皮细胞则发生变性、坏死和增生。作者认为,食管中幽门螺杆菌的感染与食管癌的发生发展有关。 In order to determine whether Hp infection was associated with esophageal cancer,43 cases of esophageal cancer and 170 normal subjects were recruited.Biopsies were taken from esophagus,antrum and duodenum for rapid ureas test. Hp in esophageal cancer biopsies were observed by electromicroscope for macroscopical and pathological study.The results showed:① the infection rate of esophageal Hp among the normal population was 25.3%, while it was as high as 90.7% in cancer patients;② Hp infection caused denaturation,necrosis and proliferation in epithelial cells.It is suggested that Hp infection in esophagus is associated with the incidence and development of esophageal cancer.
出处 《实用癌症杂志》 1998年第1期34-35,共2页 The Practical Journal of Cancer
关键词 食管肿瘤 幽门螺杆菌感染 病因 Helicobacter pylori Esophageal cancer
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