2型糖尿病患者并发脑梗死危险因素分析

A Study on the Risk Factors of Cerebral Infarction as Complication of Type 2 Diabetes Mellitus Patients

目的:探讨2型糖尿尿(DM)患者并发脑梗死(CI)的危险因素,为其预防及治疗CI提供了客观依据。方法:收集119例急性CI患者,分为2型DM合并急性CI组55例(A组)与非DM合并急性CI组64例(B组)分析DM并发CI患者的危险因素。结果:A组患者收缩压、空腹及餐后2小时血糖、甘油三酯、总胆固醇、低密度脂蛋白及同型半胱氨酸明显升高;高密度脂蛋白显著降低。通过Logistic多元回归分析显示,同型半胱氨酸、餐后2小时血糖、总胆固醇与其它引起DM血管并发症的高危因素无相关性。结论:高血压、高血糖、高血脂是DM合并CI患者的高危因素;高同型半胱氨酸血症、餐后2小时高血糖及高总胆固醇是独立危险因素。

Objective： The research is to investigate risk factors in diabetic cerebral vascular disease （DCD）. We hope it will provide objective bases for the clinical treatment of DCD. Methods： 119 patients were eligible for the criteria that the patients were admitted with acute stroke in 14 days. Of all patients, 55 patients with DCD were made as observation group, 64 patients with NDCD were made as control group. The risk factors of DCD were studied by logistic regression analysis. Results：The observation group＇s SP, FBG, 2hPG, TG, TC, LDL and Hcy were significantly higher than the control group＇s（P 〈 0.05）.The observation group＇s HDL was significantly lower than the control group＇s（P 〈 0.05）. The logistic multiple regression analysis indicated that there was no relation between Hcy, 2h PG, TC and other risk factors. Conclusion： Hypertension, hyperglycemia, hypertipemia are the risk factors ofDCD. Hcy, 2hPG and TC are the independent risk factors.