原发性高血压患者踝臂指数与高敏C反应蛋白的关系

The Relationship between Ankle-Brachial Index and Hypersensitive C-reactive Protein in the Primary Hypertension Patients

目的:探讨原发性高血压患者踝臂指数(ABI)与高敏C反应蛋白(hs-CRP)的关系。方法:采用横断面研究的方法,对255名患者进行甘油三脂(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、血糖、肝肾功能、踝臂指数(ABI)的测定,并测量血压,计算体重指数(BMI)。根据ABI的水平将患者分为A组(ABI≤0.90)和B组(ABI>0.90)。结果:(1)ABI不同的患者在年龄、SBP,BMI、TG、TC、HDL-C、LDL-C方面存在差异,差异有统计学意义:(2)ABI低的hs-CRP水平明显高于ABI高组,其差异有统计学意义。结论:可应用ABI这一简便无创的指标,结合hs-CRP的检测及时发现高血压患者存在的动脉硬化,以期进行更好的干预与治疗。

Objective： To study the relationship between Ankte-Brachial Index （ABI） and hypersensitive C-reactive protein （hs-CRP） in the primary hypertension patients. Methods： A cross-sectional study was carried outamong 255 patiens. Such examination as triglyeerides （TG）, total cholesterol （TC）, high-density lipoprotein （HDL - C）, low density lipoprotein cholesterol （LDL-C）, blood sugar, the kidney function, ankle-Braehial index （ABI） were performed.And blood pressure, body mass index （BMI） were measured.The patients were divieded into two groups as A group（ABI≤0.90） and B group（ABI〉0.90） according to the levels of ABI. Results：There are differences between two groups, patients in age, ABI, SBP, BMI, TG, TC, HDL-C and LDL-C. The difference was statistically signifyeant.The level of ABI in A group is obviously higher than that in B group.The difference was statistically significant. Conclusions：Combining hs-CRP ,ABI can be applied to detect atheroscterosis in patients with primary hypertension as a simple noninvasive index.So the primary hypertension patients can acquired better intervention and treatment.