扩张型心肌病患儿室性早搏与心率变异性相关性研究

Relationship between ventricular premature beats and heart rate variability in children with dilated cardiomyopathy

目的探讨扩张型心肌病(DCM)患儿室性早搏与心率变异性的关系。方法采用TLC3000A十二导动态心电仪,对30例正常儿童和65例DCM患儿进行动态心电分析。DCM组分为室早组和非室早组,室性早搏组按室早发生频率不同分为A组(偶发)、B组(频发)、C组(联律.多形.成对.室速),对各组进行心率变异(HRV)分析。结果DCM患儿室早各组和非室早组HRV与对照组比较差异有显著性(P<0.01);非室早组和室早A组HRV值差异无显著性(P>0.05);室早B组及C组与非室早组比较HRV明显下降,差异有显著性,且室早各组HRV依次下降,各指标组间均有显著性差异(P<0.05)。结论DCM患儿HRV值与室性早搏的严重程度有一定相关性,HRV值对DCM患儿并发室性心律失常的诊断有一定价值,也可作为预测DCM预后的一项指标。

Objective To study the relationships between ventricular premature beats and heart rate variability in children with dilated cardiomyopathy（DCM）.Methods Sixy-five children with DCM were divided into the group with no ventricular premature beats and the group with ventricular premature beats.The latter were divided into group A group B and group C basised on the different frequency of ventricular premature beats.Thirty healthy children served as the control group.All children＇s HRV parameters were measured and studied.Results Compared with control group,there were significant differences in HRV parameters with the group with no ventricular premature beats,groupA,group B and group C with analysis of variance（P〈0.01）,and a statistical significance between any two groups among group A,B and C in any HRV parameter（P〈0.05）.Conclusion The HRV parameters of children with DCM is associated with the level of ventricular premature beats.HRV may have a clinical compliance on the prognisis of DCM children.