期刊文献+

Ephb4基因多态性与非小细胞肺癌的关系 被引量:1

原文传递
导出
摘要 目前,人类功能基因组学及疾病基因组学已进入多基因疾病研究领域,而肿瘤被认为是多基因疾病,病因及发病机制尚不完全清楚。单核苷酸多态性(single nucleotide polymorphism,SNP)主要指由基因组核苷酸水平上的变异引起的DNA序列的多样性,是受到高度重视的新一代遗传标志,将构成今后基因组学研究的主要工具。
出处 《中华肿瘤杂志》 CAS CSCD 北大核心 2009年第10期778-779,共2页 Chinese Journal of Oncology
基金 国家自然科学基金(30672400)
关键词 非小细胞肺 Ephb4基因 单核甘酸多态性 Carcinoma,non-small cell lung Ephb4 gene Single nucleotide polymorphism
  • 相关文献

参考文献6

  • 1Spinola M, Meyer P, KatrLrnerer S, et al. Association of the PDCD5 locus with lung cancer risk and prognosis in smokers, J Clin Oncol, 2006, 24 : 1672-1678.
  • 2Mountain CF. Revisions in the international system for staging lung cancer. Chest, 1997, 111 : 1710-1717.
  • 3Ihde DC. Chemotherapy of lung cancer. N Eugl J Med, 1992, 327 : 1434-1441.
  • 4Hung RJ, Christiani DC, Risch A, el al. International lung cancer consortium : pooled analysis of sequence variants in DNA repair and cell cycle pathways. Cancer Epidemiol Biomarkers Prev, 2008, 17:3081-3089.
  • 5McKay JD, Hung RJ, Gaborieau V, et al. Lung cancer susceptibility locus at 5p15.35. Nat Genet, 2008, 40 : 1404-1406.
  • 6Loeb LA. A mutator phenotype in cancer Cancer Res, 2001, 61: 3230-3239.

同被引文献15

  • 1尹智华,李鸣川,崔泽实,何钦成,周宝森.Relationship between ERCC2 Polymorphism and Risk of Lung Cancer in Chinese Nonsmoker[J].Chinese Journal of Cancer Research,2007,19(3):184-188. 被引量:2
  • 2Therasse P,Arbuck SG,Eisenhauer EA. New guidelines to evaluate the response to treatment in solid tumors.European Organization for Research and Treatment of Cancer,National Cancer Institute of the United States,Nationl Cancer Institute of Canada[J].Journal of the National Cancer Institute,2000,(03):205-216.
  • 3Giaccone G,Herbst RS,Manegold C. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer:A phase Ⅲ tria-NTACT1[J].Journal of Clinical Oncology,2004,(05):777-784.
  • 4Herbst RS,Giaccone G,Schiller JH. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer:A phase Ⅲ tria-NTACT 2[J].Journal of Clinical Oncology,2004,(05):785-794.
  • 5Riely GJ,Rizvi NA,Kris MG. Randomized phase Ⅱ study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer[J].Journal of Clinical Oncology,2009,(02):264-270.doi:10.1200/JCO.2008.17.4656.
  • 6Shepherd FA,Rodrigues Pereira J,Ciuleanu T. Erlotinib in previously treated non-small-cell lung cancer[J].New England Journal of Medicine,2005,(02):123-132.
  • 7Tsao MS,Sakurada A,Cutz JC. Erlotinib in lung cancer molecular and clinical predictors of outcome[J].New England Journal of Medicine,2005,(02):133-144.
  • 8ESEL. Gefitinib plus best supportive care in previously treated patient with refractory advanced non-small-cell lung cancer:result from a randomized,placebo controlled,multicentre study (Iressa Survival Evaluation in Lung Cancer)[J].Lancet,2005,(9496):1527-1537.doi:10.1016/S0140-6736(05)67625-8.
  • 9Kobayashi S,Boggon TJ,Dayaram T. EGER mutation and resistance of non small lung cancer to gefitinib[J].New England Journal of Medicine,2005,(08):786-792.
  • 10Pao W,Miller VA,Politi KA. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain[J].PLOS MEDICINE,2005,(03):e73.

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部