组织多普勒成像评价2型糖尿病患者左心室纵向收缩功能

Evaluation of left ventricular systolic function with tissue Doppler imaging in patients with type 2 diabetes

目的探讨组织多普勒成像技术(TDI)对评价2型糖尿病患者左心室纵向收缩功能改变的临床应用价值。方法对42例2型糖尿病患者和25名健康志愿者行组织多普勒超声心动图检查,测量左心室各室壁基底段、中间段、心尖段共18个节段的心肌收缩期峰值运动速度(Sm)、位移值(Dm)及应变率(SRs)。结果两组糖尿病患者心肌收缩期最大位移和峰值应变率均较正常对照组有明显减低(P<0.01);合并高血压组左心室壁中间段心肌收缩期峰值运动速度也较对照组明显减低(P<0.05)。结论TDI技术为糖尿病心脏病变左心室收缩功能的早期检测提供了一种无创方法,局部心肌收缩期最大位移及峰值应变率能够成为检测糖尿病患者左心室收缩功能变化较敏感指标。

Objective To evaluate the clinical application of the tissue Doppler imaging （TDI） in investigating the cardiac longitudinal systolic function in the patients with type 2 diabetes mellitus. Methods Forty-two patients with type 2 diabetes mellitus and 25 volunteers underwent TDI. The long axis myocardial peak systolic velocity （Sm）, displacement （Dm） and strain rates （SRs） of 18 segments in different left ventricular walls were measured. Results The Dm and SRs of left ventricular wall in diabetic group dramatically decreased （P〈0.01）. Meanwhile, the diabetic combined hypertension group had much lower Sm of ventricular middle segments than the control group （P〈0. 05）. Conclusion The stain rate and tissue tracking are sensitive and reliable to evaluate the early local cardiac systolic function in the patients with diabetes mellitus. TDI can be used as an noninvasive method to detect early systolic dysfunction.