应变率评价冠心病患者冠脉搭桥术后左心房收缩功能

Evaluation of left atrial systolic function with strain rate imaging in patients with coronary heart disease after coronary artery bypass grafting

目的探讨冠心病患者冠脉搭桥(CABG)术后左心房收缩功能的变化。方法对23例冠心病患者,分别于CABG术前、术后1周、1个月和3个月应用应变率成像(SRI)技术定量评价左心房收缩功能。结果与术前比较,术后1周E/A、LVEF、LAFS、AEF和SRa差异无统计学意义(P>0.05),术后1个月E/A和LVEF升高,LAFS、AEF和SRa降低,差异均有统计学意义(P<0.05);术后3个月上述指标变化更明显,差异均有统计学意义(P<0.01)。与术前比较,术后1个月、3个月LVEF的变化率分别与SRa的变化率呈显著负相关(r=-0.751,-0.783;P均<0.01)。结论CABG术可影响冠心病患者左心房收缩功能,表现为辅泵功能减低。应用SRI技术可以评价左心房收缩功能,动态观察CABG手术前、后左心房收缩功能的变化。

Objective To explore the changes of left atrial systolic function in patients with coronary heart disease after coronary artery bypass grafting （CABG）. Methods Strain rate imaging （SRI） was performed on 23 patients with coronary heart disease before CABG, 1 week, 1 and 3 months after CABG to evaluate left atrial systolic function quantitatively. Results No significant change of left atrial systolic function was detected 1 week after CABG （P〉0.05）. E/A and LVEF increased, LAFS, AEF and SRa decreased 1 month after CABG compared with those before CABG （P〈0.05）. Three months after CABG, changes turned more significantly （P〈0.01）. Left ventricular ejection fraction （LVEF） increased 1 and 3 months after CABG, and its changing rate negatively correlated with those of Sra （r=-0. 751, -0. 783; all P〈0.01 ）. Conclusion Left atrial systolic function is affected by CABG, presenting as decrease of pump function. SRI can be used to evaluate the atrial systolic function quantitatively and monitor the changing of left atrial systolic function dynamically after CABG.