苎麻根化学成分研究

Chemical constituents of roots of Boehmeria nivea

目的:研究荨麻科Urticaceae苎麻属Boehmeria植物苎麻Boehmeria nivea根中的化学成分。方法:利用各种柱色谱方法和制备液相进行分离纯化,通过理化性质及波谱分析鉴定单体成分的化学结构。结果:从苎麻根醋酸乙酯部位分离得到7个化合物,分别鉴定为委陵菜酸(1),常春藤皂苷元(2),马斯里酸(3),2α-羟基乌苏酸(4),反式对羟基桂皮酸(5),2,4,4′-三羟基查耳酮(6),芦丁(7)。结论:化合物1～7为首次从该属植物中分离得到。

Objective：To investigate the chemical constituents from roots of Boehmeria nivea. Method：The constituents were isolated by repeated column chromatography and preparative liquid chromatography; and their structures were elucidated by chemical properties and spectroscopic analyses. Result：Seven compounds were isolated and their structures were identified as tormentic acid （1）,hederagenin （2）,maslinic acid （3）,2α-hydroxyursolic acid （4）,trans-p-hydroxycinamic acid （5）,2,4,4＇-trihydroxychalcone （6）,rutin （7）. Conclusion：Compounds 1-6 were obtained from this genus for the first time.