云南香格里拉县健康成人静脉血红细胞分析参考范围调查

Research on reference range of venous red blood cell measured by automated haematology analyzer for healthy adults in Shangri-la county of Yunnan province

目的建立云南省迪庆藏族自治州香格里拉县健康成人静脉血红细胞（RBC）分析参数的参考范围。方法按随机化原则挑选并采集上述地区412名健康成人静脉血，男210名，女202名，以Beckman—Coulter AC．Tdiff2自动血液分析仪作RBC参数检测后行统计学分析并与对照资料作对比。结果各项RBC参数的参考范围如下：RBC计数男性为4．31—6．54×10^12／L，女性为4．15—5．66×10^12／L；血红蛋白（Hb）浓度男性为134～202g／L，女性为124～174g／L；红细胞压积（HCT）男性为37．9～61．3％，女性为37．6～50．7％；红细胞平均血红蛋白含量（MCH）男性为25．3～36．0Pg，女性为26．2～34．3Pg；红细胞平均血红蛋白浓度（MCHC）男性为306～379g／L，女性为312～367g／L；红细胞平均体积（MCV）男性为76．5～102．6n，女性为79．0～99．3n；与对照资料相比RBC、Hb、HCT显著增高（P〈0．05），MCV、MCHC差异有统计学意义（P〈0．05），MCH差异无统计学意义（P〉0．05）。结论根据目前的临床观察，确定的香格里拉县健康人的红细胞参考范围可用于该地区人群的临床诊断、治疗和体检等医疗卫生实践：

Objective To establish the reference range of venous red blood cell （ RBC ） measured by automated haematology analyzer for healthy adults in Shangri-la county of Diqing Tibetan Autonomous Prefecture, Yunnan province. Methods 412 healthy adults were randomly chosen from the above-mentioned area. Their venous blood samples were collected for routine analysis by Beckman-Coulter AC. T diff 2 automated haematology analyzer. The results were analysed statistically and compared with reference materials. Results The ranges of RBC were 4.31-6.54 × 10^12/L in males and 4.15-5.66 × 10^12/L in females. The hematocrits （HCT） were 37.9-61.3% in males and 37.6-50.7% in females. The ranges of hemoglobin （Hb） were 134-202 g/L in males and 124-174 g/L in females. The ranges of mean corpuscular hemoglobin （MCH） were 25.3-36.0 pg in males and 26.2-34.3 pg in females. The ranges of mean corpuscular hemoglobin concentration （MCHC） were 306-379 g/L in males and 312-367 g/L in females. The ranges of mean corpuscular volume （MCV） were 76.5-102.6 fl in males and 79.0-99.3 fl in females. Comparing with reference results, RBC, Hb, and HCT increased remarkably （P 〈 0.05 ）. There was statistical difference for MCV and MCHC （ P 〈 0.05 ） , and no statistical difference for MCH （ P 〉 0. 05 ）. Conclusions According to the clinical observation by now, the reference range of venous RBC for healthy adults of Shangri-la county can be applied to medical health practice for clinical diagnosis, treatment and health-examination.