芬太尼复合罗哌卡因麻醉用于老年下肢手术的效果及对应激的影响

The analgesic effects and effects on stress response of fentanyl combined with ropivacaine in the crura operations of old patients

目的观察芬太尼复合罗哌卡因麻醉用于老年下肢手术的效果及对应激的影响。方法50例老年下肢手术患者,随机分为两组:罗哌卡因复合芬太尼组(观察组)和罗哌卡因组(对照组)。观察两组患者麻醉效果,测定麻醉前、切皮后60、90min的皮质醇、胰岛素和血糖水平。结果观察组感觉维持时间长于对照组。切皮后60、90min的皮质醇和血糖水平对照组高于观察组。观察组血糖浓度在切皮后60、90min与术前相比无明显变化,对照组血糖浓度在切皮后60、90min与术前比较均明显增高。结论芬太尼复合罗哌卡因麻醉效果良好,并能够减轻下肢手术时应激反应。

Objective To observe the analgesic effects and effects on stress response of fentanyl combined with ropivacaine in the crura operations of old patients. Methods 50 old patients scheduled for the crura operation were divided randomly into two groups：ropivacaine （control group）and that with fentanyal （observation group）. The analgesic effects were evaluated. Cortisol, insulin and blood sugar level at defined time were measured and compared. Results The sense lasting time in the observation group was longer than that in the control group. 60 min and 90 min after skin incision,the levels of cortisol and blood sugar in the observation group were higher than those in the control group. Blood sugar content did not change significantly 60 min and 90 min after skin incision in the observation group,but increased significantly in the control group. Conclusion Ropivacaine combined with fentanyal was effective and could relieve the increase of cortisol and blood sugar content resulting from stress response in the crura operations of old patients.