血液净化联合激素抢救毒蕈中毒性急性肾衰竭的临床研究

A clinical study to blood purrification and glucocorticoid in the rescue acute renal failure because of toadstool

目的：探讨采用血液灌流串联血液透析联合小剂量激素抢救毒蕈致中毒性急性肾衰竭的疗效。方法：血液灌流串联血液透析每次3h,1次/d,小剂量糖皮质激素3～5d。监测血清ALT、AST、BUN、Cr及尿量恢复情况。结果：12例患者共行60次血液灌流串联血液透析治疗,10例患者在治疗后第5天各项指标基本恢复正常。尿量增加于治疗后平均3.6d出现,进入多尿期平均5.3d。结论：血液灌流串联血液透析,联合小剂量糖激素治疗毒蕈致中毒性急性肾衰竭的疗效肯定。

Objective： To explore the curative effect of hemoperfusion cascade hemodialysis to rescue acute renal failure because of toadstool. Methods ：All patients were treated with hemoperfusion cascade hemodialysis one time a day,3 hours/time. They were treated with minidose glucocorticoid 3-5 days. Monito indexs ：blood serum ALT. AST. BUN. Cr and urine volume reablement. Results： 12 patients were treated with hemoperfusion cascade hemodialysis 60 times in all. 10 patients indexs rebound normal after 5 days. Their urine volume increased in 3.6 days and came to diuresis stage in 5. 3 days medially. Conclusion： It was affirmative that hemoperfusion cascade hemodialysis and minidose glucocorticoid to rescue acute renal failure because of toadstool.