复方洁霉素滴鼻液细菌微生物限度验证

Validation of Method in Bacterial Microorganisms Limits for Compound Lincomycin

目的建立复方洁霉素滴鼻液的微生物检查法。方法通过对供试品的离心处理后,联合培养基稀释法,建立复方洁霉素滴鼻液微生物限度验证方法。结果采用上述实验方法,5种验证用菌的回收率都在70%以上。结论检查复方洁霉素滴鼻液微生物限度可用离心沉淀集菌法联合培养基稀释法。

Objective To establish a microbial test method for compound lincomycin nasal drops. Methods Validation the microbial limit tests by the method of centrifuge with drops and culture cultivatable medium methods. Results The recoveries for 5 kind of bacteria used to verify were more than 70% when it used the above method. Conclusion To examine microbial limit test of compound lincomycin nasal drops used to centrifuge subside method united cultivvatable medium method.