龙胆泻肝丸联合抗病毒及肋间神经阻滞治疗带状疱疹性神经痛

Combination of Longdanxiegan Pills,Antiviral Drug and Intercostal Nerve Block as a Therapy for Herpes Zoster Neuralgia

目的观察龙胆泻肝丸口服联合抗病毒及镇痛药物治疗带状疱疹性神经痛的临床效果.方法60例带状疱疹神经痛患者随机分为2组,A组：龙胆泻肝丸＋肋间神经阻滞＋抗病毒治疗;B组：单纯抗病毒治疗.以视觉模拟评分（VAS）和睡眠质量评分（QS）评定治疗效果.结果治疗后从即刻开始至观察期（20 d）结束,A组VAS评分较治疗前显著降低（P〈0.01）,睡眠状况也明显改善（P〈0.01）;而B组患者仅在第15天开始疼痛有所减轻,睡眠状况好转.结论采用龙胆泻肝丸口服＋肋间神经阻滞行镇痛治疗、联合抗病毒药物治疗对带状疱疹患者的疼痛缓解和睡眠质量改善有很好的疗效.

Objective To observe the clinical effect of combination of Longdanxiegan pills,antiviral drug and intercostal nerve block on herpes zoster neuralgia. Method 60 cases with herpes zoster neuralgia were randomly divided into two groups,group A：Longdanxiegan pills,antiviral drug and intercostal nerve block; group B：antiviral drug. The therapy effect was evaluated with visual analogue scale and quality of sleep. Results The score of visual analogue scale in group A reduced obviously than before （P 〈 0.01 ） ,quality of sleep improved obviously （P 〈 0. 01） ;The patients in group B began to reduce the pains and improved the quality of sleep from the 15th day. Conclusion Combination of Longdanxiegan pills,ant/viral drug and intercostal nerve block as a therapy for herpes zoster neuralgia have better effect on relieving pain and improving quality of sleep.