心理干预对老年甲状腺功能减退抑郁患者康复的影响

Influence of psychological interventions on aged depressive patients with post-hypothyroidism

目的探讨心理干预对老年甲状腺功能减退症（甲减）抑郁患者临床康复的影响。方法42例老年甲减后抑郁患者按随机数字表法分为2组，每组21例。2组患者均接受常规抗甲减药物、抗抑郁及康复治疗，心理干预组同时进行心理干预，分别进行汉密顿抑郁量表（HAMD）、神经功能缺损评分（NFA）、Barthel生活能力指数（BI）及运动功能评分（FMA）测评。结果2组治疗前各项评分差异无显著性（P〉0．05）。治疗4周后对照组HAMD评分为[（15．5±3．5）分]、NFA为（15．0±6．3）分、BI为（38．5±20．6）分、FMA为（43．9±21．2）分；心理干预组HAMD评分（10．2±3．2）分、NFA为（11．6±5．9）分、B1为（50．2±21．8）分、FMA为（56．6±20．6）分，2组差异具有显著性（P〈0．05）。结论心理干预能有效缓解老年甲减后患者的抑郁情绪，提高康复效果。

Objective To evaluate the efficiency of psychological interventions on aged depressive patients with post-hypothyroidism. Methods 42 patients were investigated by using case-control study. 21 of them were recruited as the experimental group and control group. Two groups received anti-hypothyroidism ＆ anti-depressant medications and rehabilitation treatment. At the meantime the experimental group received psychological interventions. Before and after treatment,2 groups were evaluated by Hamilton Depression Rating Scales （HAMD） , Fugl-Meyer Assessment（ FMA ）, Neurological Function Deficits Assessment （ NFA ）, Barthel （ Barthel Index, BI ）. Results Before intervention,the score of HAMD, NFA, BI, FMA was （ 15.5 ± 3.5 ）, （ 15.0 ± 6.3 ）, （ 38.5 ± 20.6） , （43.9 ± 21.2 ） respectively in control group. After intervention, the score of HAMD, NFA, BI, FMA was （ 10.2 ± 3.2 ）, （ 11.6 ± 5.9 ）, （ 50.2 ± 21.8 ）, （ 56.6 ± 20.6 ） respectively in control group. Compared with control group, scores of the scales were significant difference between two groups after 4 weeks psychological interventions （P 〈 0.05 ）. Conclusion The psychological interventions are effective in improving activities of daily living on aged depressive patients with post-hypothyroidism.