湿疹患者生活质量量表的编制和考评

Development and evaluation of quality of life scale for patients with eczema

目的编制湿疹患者生活质量量表。方法编制湿疹患者生活质量初始量表，采用初始量表对湿疹患者进行实测，收集有效问卷351份。采用5种方法进行条目分析，由保留条目组成量表测试版。并对量表进行信度和效度考评。结果（1）编制出28个条目的湿疹生活质量量表（eczema quality of life scale，EQOLS），分别属于由疾病、心理、生理、社会4个维度和1个反应总体生活质量的条目。（2）EQOLS总量表重测信度0．912，Cronbaeh’s α系数0．935，分半信度系数0．905。（3）EQOLS总分与皮肤病生活质量指数（Dermatology Life Quality Index，DLQI）总分、病情（eczema area and severity index，EASI）评分值、反映总体生活质量条目A43值，相关系数分别为0．795，0．805，0．812，（P〈0．01）。患者治疗1周前后EQOLS值有显著差异（P〈0．01）。（4）验证性因子分析：拟合优度的卡方检验χ^2／df=2．211，比较拟合指数CFI=0．902，非正规划指数NNFI=0．892，近似均方根残差RMSEA=0．059。结论EQOLS具有较好的信度、效度，可以用于湿疹患者生活质量的测评。

Objective To develop a specific quality of life scale for eczema patients（EQOLS）. Method The theory and methodology had been adopted before the item pool formed. Five methods had been used in the item analyzing with the data of 351 eczema patients had been recruited. And the reliability and validity of the scale were also tested. Result The eczema quality of life scale with 28 items was developed, including 4 domains （ morbid, physical, social psychological） and one item on general QOL. The test-retest correlation coefficient, Cronbach＇ s Alpha coefficient and split-half reliability coefficient of EQOLS were 0. 912,0. 9346 and 0. 9046, respectively. The EQOLS scores were significantly decreased after one week＇ s treatment （P 〈 0. 01 ）. There was a significantly positive correlation between EQOLS and EASI scores （ r = 0. 805, P 〈 0.01 ）. Confirmatory factor analysis showed that χ^2/df=2. 211 ,CFI =0. 902,NNFI =0. 892,RMSEA =0. 059,respectively. Conclusion EQOUS is reliable, valid and sensitive, and can be used to evaluate the quality of life for eczema patients.