依达拉奉联合丁苯酞治疗脑梗死疗效观察

目的研究依达拉奉与丁苯酞联合治疗急性脑梗死的疗效。方法90例急性脑梗死患者随机分为常规药物加依达拉奉联合丁苯酞的治疗组(30例)和单独使用依达拉奉加常规药物的对照组A(30例)、丁苯酞加常规药物的对照组B组(30例),比较治疗7d、14d的ESS评分和BarthelADL指数评分。结果联合治疗组较对照组A、B治疗后ESS评分、BarthelADL指数评分均改善明显P<0.05,有统计学意义。结论依达拉奉联合丁苯酞治疗脑梗死能够较单独使用更有效地减少治疗后7d和14d的神经功能缺损。

Objective To observe the efficacy of edaravone comblined with Butyphthalide in treatment of acute cerebral infarction. Methods 90 patients with acute cerebral infarction were randomly divided into edaravone combined with Butylphthalide group and conventional medicine treatment group （30case）. Edaravone and conventional drug （the placebo group A, 30case）, Butylphthalide and conventional drug（ the placebo group B,30 case）. Comparing the Ess and Barthel ADL index scores, at the 7 th, 14 th after treatment. Results The ESS and Barthel ADL index scores in treatment group were improved significantly than that in the control group A, B （P 〈 0. 05）, there was asignificant difference between treament group and placebogroup. Conclusion Edaravone combined with Butylphthalide in treatment of cerebral infarction can be more effective to reduction at the 7 th and 14 th after theatment of the neurological deficit than Edaravone treamnet.