捡了西瓜,就该丢掉芝麻吗——浅谈医源性Wernicke脑病

Pick up the Watermelon While Lose the Sesame-about Iatrogenic Wernicke's Encephalopathy

探讨医源性Wernicke脑病(WE)的病因、临床及磁共振图像特点,回顾性分析6例医源性WE病例。医源性WE病前均有禁食史,其临床表现多样。磁共振图像为中脑导水管周围T2WI及Flair高信号。大部分病例补充维生素B1后可好转。提示医源性禁食导致体内维生素B1耗竭是医源性WE的病因,及时补充维生素B1是预防及治疗本病的关键。

This study was to investigate iatrogenic wernicke＇ s encephalopathy（WE） on its etiologies, clinical and brain magnetic resonance imaging （ MRI） features. Retrospective analysis was conducted on 6 cases of iatrogenie WE. There was iatrogenic fasting before WE in hospital, clinical manifestations were complicated. Brain MRI examination showed high signals in T2 and Flair image below the periaqueductal mesencephalon. With vitamin B1 therapy, most patients improved. Which suggest iatrogenic fasting resulting in vitamin B1 deficiency in most cases. Timely supply of vitamin B1 is the key to the prevention and therapy of WE.