丙泊酚伍用不同药物在无痛人工流产术中的应用价值

The application of propofol combined with different drugs in the painless induced abortion

目的:寻找安全有效的人工流产(人流)麻醉用药方案。方法:自愿行无痛人流300例,随机分为3组。A组:丙泊酚+芬太尼+麻黄碱;B组:丙泊酚+芬太尼+利多卡因;C组:丙泊酚+芬太尼+麻黄碱+利多卡因。比较三组用药方案在缓解丙泊酚注射痛及对呼吸循环功能、麻醉效果及苏醒时间的影响。结果:C组较A、B组明显缓解丙泊酚注射痛,麻醉效果显著提高(P<0.05),且呼吸循环稳定,不良反应显著减少,缩短了麻醉苏醒时间。结论:丙泊酚伍用小剂量麻黄碱、芬太尼、利多卡因用于无痛人流,麻醉更安全、有效,苏醒更快且无或仅轻微注射痛。

Objective： To investigate an effective scheme of anaesthasia prescription for induced abortion. Methods： 300 cases of patients voluntarily on induced painless abortion operation were distinguished randomly to three groups： group A were treated with propofol, fentanyi and ephedrin; group B were treated with propofol, fentanyi and lidocaine; group C were treated with propofol, fentanyi, ephedrin and lidocaine. To observe and compare with the influence of all of the 3 prescription on relieving the injection pain of propofol and the anaesthasia effect, analepsia time, breathing function together with circulation function of patients.Results： Group C relieved the injection pain of propofol notably, so as to improve the anaesthasia effect greatly（ P 〈 0.05）, got stable breathing and circulation situation,induced the adverse effect obviously and shorten the analepsia time of anaesthesia. Conclusion： Ultilizing low dose of ephed,pentanyi,lidoeaine together with propofol during induced painless abortion resulted in a safer, more effective anaesthesia and faster analepsia as well as less injection pain.