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慢性特发性血小板减少性紫癜患者抗幽门螺杆菌治疗的效果分析 被引量：4

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摘要 目的对成人幽门螺杆菌(Hp)感染的慢性特发性血小板减少性紫癜(ITP)患者进行Hp根治,评估其对血小板的影响。方法对30例ITP患者采用前瞻性对照研究,其中19例Hp阳性的患者接受1周三联药物根治,Hp阳性的患者在第0、第2、第4、第12、第24周复查血小板(Plt)计数。结果通过三联治疗HP阳性的患者有94.7%(18/19)根治;58.8%(10/17)Hp根治的患者显示ITP治疗有效。结论对于中国人群来说,轻中度的慢性ITP患者治疗应包括检测Hp及考虑根治Hp感染。
作者 沈文香 陈敏斌 傅爱林 沈刚 徐海源 周丽娜
机构地区 昆山市第一人民医院血液肿瘤科
出处 《苏州大学学报（医学版）》 CAS 北大核心 2009年第4期711-712,共2页 Suzhou University Journal of Medical Science
关键词 特发性血小板减少性紫癜 幽门螺杆菌 根治
分类号 R544.6 [医药卫生—心血管疾病]
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参考文献7

  • 1Emilia G, Luppi M, Zucchini P, et al. Helicobacter pylori infection and chronic immune thrombocytopenic purpura: long-term results of bacterium eradication and association with bacterium virulence profiles [J] . Blood, 2007,110 (12):3833-3841.
  • 2Kodama M, Kitadai Y, Ito M, et al. Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura [J] . Helicobacter, 2007, 12(1 ):36-42.
  • 3Asahi A, Kuwana M, Suzuki H, et al. Effects of a Helicobacter pylori eradication regimen on anti-platelet autoantibody response in infected and uninfected patients with idiopathic thrombocytopenic purpura [J] . Haematologica, 2006,91 ( 10):1436-1437.
  • 4Franchini M, Cruciani M, Mengoli C, et al. Effect of Helicobacter pylori eradication on platelet count in idiopathic thrombocytopenic purpura: a systematic review and meta- analysis[J]. J Antimicrob Chemother, 2007,60(2):237-246.
  • 5Veneri D, Krampera M, Franchini M. Helicobacter pylori infection and idiopathic thrombocytopenic purpura: description of 21 newly diagnosed cases [J]. Haematologica, 2004,89 (4) :ECR08.
  • 6Stasi R, Rossi Z, Stipa E, et al. Helicobacter pylori eradication in the management of patients with idiopathic thrombocytopenic purpura [J]. Am J Med, 2005,118 (4): 414-419.
  • 7Suzuki T, Matsushima M, Masui A, et al. Effect of Helicobacter pylori eradication in patients with chronic idiopathic thrombocytopenic purpura-a randomized controlled trial [J]. Am J Gastroenterol, 2005,100(6):1265-1270.

同被引文献28

  • 1Gasbarrini A, Franceschi F, Tartaglione R, et al. Regression of autoimmune thrombocytopenia after eradication of Helicobacter pylori[ J]. Lancet, 1998, 352(9131 ) :878.
  • 2Takahashi T, Yujiri T, Tanizawa Y. Helicobacter pylori and chronic ITP: the discrepancy in the clinical responses to eradication therapy might be due to differences in the bacterial strains [J].Blood, 2004, 104 (2) :594.
  • 3Franchini M, Veneri D. Helicobacter pylori-associated immune thrombocytopenia[J]. Platelets, 2006 , 17 (2) :71 - 77.
  • 4Suzuki T, Matsushima M, Masui A, et al. Ettect of Helicobacter priori eradication in patients with chronic idiopathic thrombocytopenic purpura-a randomized controlled trial [J]. Am J Gastroenterol, 2005,100(6) :1265 -1270.
  • 5Stasi R, Sarpatwari A, Segal JB, et al. Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura: a systematic review[J]. Blood, 2009, 113 (6) : 1231 - 1240.
  • 6Jarque I, Andreu R, Llopis I, et al. Absence of platelet response after eradication of Helicobacter pylori infection in patients with chronic idiopathic thrombocytopenic purpura [ J ]. Br J Haematol, 2001, 115 (4) : 1002 - 1003.
  • 7Michel M, Cooper N, Jean C, et al. Does Helicobater pylori initiate or perpetuate immune thrombocytopenic purpura[J].Blood, 2004,103(3):890 -896.
  • 8Takahashi T, Yujiri T, Shinohara K, et al. Moleucular mimiery by Helicobaeter pylori eagA protein may be involved in the pathogenesis of Helicobacter pylori-associated chronic idiopathic thrombocytopenic purpura [ J ]. Br J Haematol,2004,124( 1 ) :91 - 96.
  • 9Michel M, Khellaf M, Desforgges L, et al. Autoimmune thrombocytopenic purpura and Helicobacter pylori infection[J]. Arch Intern Med,2002,162(9) :1033 - 1036.
  • 10Perez-Perez GI, Bhat N, Gaensbaure J, et al. Countryspecific constancy by age in cagA^+ proportion of Helicobacter pylori infection [ J ]. Int J Cancer, 1997,72 ( 3 ) : 453 - 456.

引证文献4

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苏州大学学报（医学版）
2009年 第4期

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