长期口服“偏方”对支气管哮喘重度及危重发作治疗反应的影响

Clinical observation of severe and critical bronchial asthma attacks due to long-term oral administration of folk prescriptions

目的探讨长期口服"偏方"对支气管哮喘重度及危重发作时治疗反应的影响。方法重度及危重支气管哮喘患者62例,其中服过"偏方"超过1年的患者30例作为观察组,未服药者32例作为对照组,对2组患者给予常规治疗,并把治疗前及治疗3天后的心率(HR)、呼吸频率(RR)、动脉收缩压(SP)、动脉血气分析〔氧分压(PaO2)、二氧化碳分压(PaCO2)、pH值〕进行对照分析,治疗1周后进行疗效评定。结果2组治疗3天后的HR、RR、SP及动脉血气均较治疗前有明显改善(P<0.05),但两组相比观察组较差(P<0.05),1周后的有效率2组间差异有统计学意义(P<0.05)。结论观察组对治疗的反应差,考虑由长期服用"偏方"所致,因此推广及普及哮喘的长期规范化管理是呼吸科各级医生共同努力的目标。

Objective To investigate the response to treatment and the prognosis of severe and critical bronchial asthma attacks due to long-term oral administration of folk prescriptions.Methods 62 patients with severe and critical bronchial asthma from Jan.2006 to Dec.2008 were selected,of whom 30 patients with a history of folk prescription administration for more than 1 year were designated as the observation group,while the other 32 patients who had not taken any folk medication served as the control group.Both groups underwent routine treatment and their data as to the heart rate（HR）,respiration rate（RR）,systolic pressure（SP）,partial arterial oxygen tension（PaO2）,partial pressure of carbon dioxide in arterial blood（PaCO2） and pH were collected and compared before and 3 days after the treatment.One week later,the therapeutic evaluation was conducted.Results 3 days later the treatment,the HR,RR,SP and arterial blood gases of both groups had marked improvement（P〈0.05）,but the results in the observation group were inferior to those in the control group（P〈0.05）.One week after treatment,compared with the contrast group,the effective rate in the observation group still had obvious statistics significance（P〈0.05）.Conclusion The reason for the poor treatment effect in the observation group is due to the long-term abuse of folk prescriptions.Therefore,it is the duty and goal of doctors at all levels to promote and popularize the long-term standardized management of asthma.