面手性二芳基膦-噁唑啉配体的开发及其在不对称催化反应中的应用

Development of Planar Chiral Diarylphosphino-oxazoline Ligands and Their Applications to Asymmetric Catalysis

膦-噁唑啉配体形成的催化剂具有出色的催化活性和对映选择性,被广泛应用于各种不对称催化反应中.具有面手性的膦-噁唑啉配体是其中重要的一类.综述了面手性二芳基膦-噁唑啉配体的开发,并按反应类型介绍了它们在不对称催化反应中的应用.

Phosphino-oxazoline ligands have been widely used in a variety of transition metal catalyzed asymmetric reactions with excellent catalytic activity and enantioselectivity.Planar chiral phosphino-oxazoline ligands are of great importance among them.A comprehensive review on the development of planar chiral diarylphosphino-oxazoline ligands and their applications to enantioselective catalysis is made in this article.