血液透析在尿毒症性肺水肿治疗中的作用

The Function of the Hemodialysis in the Treatment of Pulmonary Edema in Uremic Patients

目的:探讨血液透析在尿毒症性肺水肿治疗中的作用。方法:回顾性分析96例尿毒症性肺水肿患者的临床资料,比较进行血液透析的50例患者(透析组)与未进行血液透析的46例尿毒症性肺水肿患者(未透析组)的治疗效果。结果:尿毒症性肺水肿胸部X线表现无明显特征性。透析组36例有效,有效率为72.0%,病死率为8.0%;未透析组7例有效,有效率为15.2%,病死率为47.8%,两组差异有统计学意义(P<0.01)。透析组治疗后与治疗前比较肾功能明显好转(P<0.05),与未透析组比较差异也有统计学意义(P<0.05).结论:血液透析是治疗尿毒症性肺水肿最有效的方法,早期充分血液透析可预防尿毒症肺水肿的发生,降低病死率。

Objective：To explore the function of the hemodialysis in the treatment of the pulomary edema in uremic patients. Methods： Clinical features of 96 uremic patients with pulmonary edema were retrospectively analyzed and treatment efficacy of 50 patients undergoing hemodialysis （ hemodialysis group） and 46 patients not undergoing hemodialysis （ non-hemodialysis group） was compared. Results ： Chest X-ray examination of uremic patients with pulmonary edema showed no obvious characteristic features. In dialysis group, 36 patients showed improvement （72.0%） and mortality rate was 8.0% while in non-hemodialysis group,7 patients showed improvement （15.2%） and mortality rate was 47.8% with differences of statistical significance （ P 〈 0.01 ）. In hemodialysis group, renal function markedly improved after treatment （ P 〈 0.05 ） and the difference was statistically significant when compared with that of non-dialysis group （ P 〈 0. 05 ）. Conclusion ： For uremic patients with pulmonary edema, hemodialysis is the most effective treatment and adequate early hemodialysis in uremic patients can prevent the occurrence of pulmonary edema and reduce mortality.