期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

创伤性脑损伤动物模型的研究进展 被引量：3

Advance in Animal Models of Traumatic Brain Injury(review)
下载PDF
导出
摘要 建立良好的创伤性脑损伤动物模型对其机制研究和治疗研究具有十分重要的意义。本文对几种主要的创伤性脑损伤动物模型的进展、制备方法、应用范围、各模型的特点和不足之处进行分析总结,并提出复制理想动物模型的几点标准。 Good animal models of traumatic brain injury have a great significance in the pathogenesis research and treatment study.This paper reveiwed development in animal models of traumatic brain injury,including preparation methods,application range,characteristics and shortcomings of each model.
作者 王娜 李林
机构地区 首都医科大学宣武医院药物研究室
出处 《中国康复理论与实践》 CSCD 2009年第10期905-907,共3页 Chinese Journal of Rehabilitation Theory and Practice
基金 北京市科委针对重大疾病的创新药物研究项目(D0206001043191)
关键词 脑损伤 创伤 动物模型 综述 brain injury trauma animal model review
分类号 R651.1 [医药卫生—外科学]
  • 相关文献

参考文献29

  • 1Atlanta National Center for Injury Prevention and Control. Report to Congress on Mild Traumatic Brain Injury in the United States: steps to prevent a serious public health problem [R]. 2003--03--05.
  • 2McCarthy M, Dikmen S, Langlois L, el al. Self-reported psychosocial health among adults with traumatic brain injury [J]. Arch Phys Med Rehabil, 2006, 87(7): 953--961.
  • 3Denny B, Russell W. Experimental cerebral concussion [J]. J Physiol, 1940, 99(1): 153.
  • 4Feeney DM, Boyeson MG, Linn RT, et al. Responses to cortical injury I. Methodology and local effects of contusions in the rat [J]. Brain Res, 1981, 211(1) :67--77.
  • 5Chen Y, Shohami E, Bass R, et al. Cerebro-protective effects of ENAT13, a novel acetyl cholinesterase inhibitor, in closed head injury in the rat [J]. BrainRes, 1998, 784(1 --2) :18--24.
  • 6Tang YP, Noda Y, Hasegawa T, et al. Effects of VA-045 on learning and memory deficits in traumatic brain injury (TBI) induced retrograde and anterograde amnesic mice [J]. BrJ Pharmacol, 1997, 122(2):257--264.
  • 7Lomnitski L, Kohen R, Chen Y, et al. Reduced levels of antioxidants in brains of apolipoprotein E deficient mice following closed head injury [J]. Phamacol Biochem Behav, 1997, 56(4):669-673.
  • 8吴旭,王保捷,张国华,官大威,汪德文,杨丽,刘长胜.大鼠脑损伤分级自由落体打击模型的建立[J].中国法医学杂志,2005,20(1):1-3. 被引量：35
  • 9Marmarou A, Foda MA, van den Brink W, et al. A new model of diffuse brain injury in rats. Part I: Path physiology and biomechanics[J]. Neurosurg, 1994, 80(2): 291--300.
  • 10Foda MA, Marmarou A. A new model of diffuse brain injury in rats. Part II: Morphological characterization [J]. Neurosurg, 1994, 80(2):301--313.

二级参考文献7

共引文献43

同被引文献52

  • 1QINXiao-song,JINKui-he,DINGBao-kun,XIEShou-fu,MAHui.Effects of extract of Ginkgo biloba with venlafaxine on brain injury in a rat model of depression[J].Chinese Medical Journal,2005(5):391-397. 被引量：8
  • 2孙良智,张柳,王守君,赵文国.大鼠股骨骨折合并脑损伤骨折愈合过程中胰岛素样生长因子Ⅰ在血清和骨痂中的表达[J].中国临床康复,2006,10(40):60-62. 被引量：32
  • 3马维,牛彦平,张华.合并脑损伤大鼠骨折愈合过程中转化生长因子β1血清含量及在骨折位点的表达[J].中国临床康复,2006,10(42):88-91. 被引量：19
  • 4Wagner A.K, Sokoloski JE, Ren D, et al. Controlled corti- cal impact injury affects dopaminergic transmission in therat striatum[J]. J Neurochem, 2005,95 (2) :457-465.
  • 5Rogers DC, Campbell CA, Stretton JL. Correlation between motor impairment and infarct volume after permanent and transient middle cerebral artery occlusion in the rat [J]. Stroke, 1997,28(10) : 2060-2066.
  • 6Gerlinde AM, Whishaw IQ. Cortical and subcortical lesions impair skilled walking in the ladder rung walking test: a new task to evaluate fore-and hindlimb stepping, placing, and co-ordination [J]. Journal of Neuroscience Methods, 2002,115(2) : 169-179.
  • 7Vorhees CV, Williams MT. Morris water maze: procedures for assessing spatial and related forms of learning and memo- ry[J]. Nature Protocols, 2006,1(2) :848-858.
  • 8Sutton RL, Lescaudron L, Stein DG. Unilateral cortical contu- sion injury in the rat: vascular disruption and temporal devel-.opment of cortical necrosis[J]. J Neurotraurna, 1993,10(2): 135-149.
  • 9Morganti-Kossmann MC, Yam E, Bye N. Animal models of traumatic brain injury:is there an optimal model to re- produce human brain injury in the [aboratory[J]? Injury, 2010,41 (Suppl 1) : 10-13.
  • 10刘媛,王莉,曾琳,等.一种改良的创伤性脑损伤模型的建立[J].2008,13(7):416-419.

引证文献3

二级引证文献15

中国康复理论与实践
2009年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部