技能训练对农村精神分裂症患者康复的作用2年随访

A Two-year Follow-up Study on Efficacy of Skills Training on Schizophrenia

目的探讨技能训练对农村精神分裂症患者康复的作用。方法将89例农村精神分裂症患者随机分为技能训练组(45例)和对照组(44例),对干预组在入组时点和随访第12个月分别进行康复技能训练12周。两组均完成了为期2年的随访。随访中对两组的精神症状(PANSS)、社会功能(SDSS),复发和就业情况进行比较。结果①两组间PANSS评分在随访第12个月、及与SDSS评分在随访第18个月技能训练组均显著低于对照组(均P<0.05);②在随访第24个月,技能训练组复发率(11.1%)低于对照组(31.8%),再就业率(37.8%)高于对照组(15.9%)(均P<0.05)。结论在药物治疗基础上,对患者进行康复技能训练能促进其病情逐步缓解、预防其病情复发和促进患者社会功能恢复。

Objective To study the efficacy of medication management,symptom management and community reentry skills-training modules to prevent rural patients with schizophrenia from relapse and increase their social function.Methods 89 subjects were randomly assigned to the skills training group（45 cases） and the control group（44 cases）.Both groups received the same treatments,but the skills training courses were given to the skills training group for twelve weeks when the subjects were addmitted into the trial and at their one-year follow-up timepoint respectively. And a two-year follow-up was carried out. All subjects were evaluated with PANSS, SDSS, relapse and employeement. Results 89 subjects had completed the study. The skills training group demonstrated clinical results significantly superior to those of the control group on overall improvement according to PANSS and SDSS. Substantially, statistically significant advantages of the skills training group were related to 1） the rate of relapse （11.1 % vs 31.8 % ）, 2） the rate of employment （37.8 % vs 15.9 % ）. Conclusion Medication management, symptom management and community-reentry skills-training modules are effective in reducing patients＇ psychiatric symptoms, preventing them from relapse and increasing their social function.