128例急性呼吸窘迫综合征患者的临床分析

Clinical analysis of 128 cases acute respiratory distress syndrome

目的比较肺部原因诱发的急性呼吸窘迫综合征和肺外原因诱发的急性呼吸窘迫综合征临床特征,为指导临床科学治疗急性呼吸窘迫综合征提供研究资料。方法128例急性呼吸窘迫综合征患者的临床资料,据病因分为急性呼吸窘迫综合征组和ARDSexp组,回顾性分析总结两组在基础疾病、预后及与全身性炎症反应综合征的关系、多器官功能障碍综合征的发生率等方面的异同点。结果①ARDSp组以肺炎最多见,ARDSexp组最多见的是脓毒症、其次是重症胰腺炎。②两组与全身性炎症反应综合征的关系方面无统计学差异。③ARDSexp组和多器官功能障碍综合征发生率、死亡率明显高于ARDSp组,差异有统计学意义(P<0.05)。结论ARDSexp组的MODS发生率、死亡率显著高于ARDSp组,但两组患者与SIRS的关系无统计学差异。

Objective To compare clinical characteristics of pulmonary - induced acute respiratory distress syndrome （ARDSp） and extrapulmonary- induced （ARDSexp） origin. Methods The clinical data of 128 hospitalized patients diagnosed as ARDS in five years from January 2003 to December 2007 were Analyzed and make group, summarize retrospectively the similarities and differences in death rate, imaging, accident rate of MODS, relationship between ARDS and SIRS etc. Results 1. The most common underlying disease for ARDSp were severe pneumonia, ARDSexp were sepsis,acute severe pancreatitis. 2. Defferences has not statistics significance in relationship between ARDS and SIRS. 3. Accident rate of MODS in ARDSexp was much higher than in ARDSp,there was significant difference between the two groups （P 〈 0.05）. Conclusions Though there was a relatively high mortality of ARDSexp in these ARDS, the relationship between ARDS and SIRS were similar in both subgroups.