老年慢性精神分裂症与Alzheimer病的认知功能筛查结果比较

Comparison of Cognitive Function between Chronic Elderly Schizophrenics and Patients with Alzheimer Disease

应用认知功能筛查量表（ＣＡＳＩ）评定４１名正常老人、８５名老年慢性精神分裂症与３５名Ａｌｚｈｅｉｍｅｒ病患者，结果显示老年慢性精神分裂症患者中约一半有认知功能缺损。认知相对保存的分裂症患者的ＣＡＳＩ总分、因子分较正常老人明显减低；认知损害的分裂症患者的认知损害模式与Ａｌｚｈｅｉｍｅｒ病的损害不同。结论：老年慢性精神分裂症患者的认知损害可能具有独特的模式，不同认知结局的精神分裂症可能存在异源性病因。

To analyze the cognitive function of chronic elderly schizophrenics,we evaluated 41 normal elderly,85 chronic elderly schizophrenics and 35 patients with Alzheimer disease using cognitive ability screening instrument Result Showed that(1) compared with normal elderly,schizophrenics remained cognitive function relatively had significant impairment yet (2) schizophrenics had deficit pattern different to that of Alzheimer disease The results suggest schizophrenia are likely to have distinctive cognitive profile and schizophrenia with different cognitive outcomes may be heterogeneous in etiology