盐城市盐都区1964～2007年霍乱病原学特征分析

Pathogenic features of cholera in Yandu District of Yancheng City in 1964～2007

目的 了解盐都区近40年霍乱流行的病原学特征与分布。方法对江苏省盐城市盐都区1964-2007年的霍乱监测资料进行描述性流行病学分析。结果1964—2007年，江苏省盐城市盐都区共检出霍乱弧菌2349株，进入90年代以后，霍乱弧菌的检出数急剧下降；80年代以前，霍乱孤菌的分布以小川血清型为主，80年代以后，优势菌株转为稻叶型；人体中分离的霍乱弧菌以流行株居多，而水源及其他外环境中分离的霍乱孤菌以非流行株居多。结论虽然盐城市盐都区近几年霍乱弧菌的检出数显著下降，但由于霍乱弧菌的变异及O139群的出现，霍乱疫情的防治仍是当地的重要公共卫生问题。

Objective To understand the etiologic and pathogenic feature of cholera in Yandu District from 1964 to 2007. Methods The data of minotoring of cholera were collected in Yandu District of Yancheng City from 1964 to 2007 and epidemiologieally analzyed. Results Totally 2 349 strains were detected in Yandu within the recent 44 years,and the detected strains of Vibrio cholera reduced rapidly in the 1990s. Ogawa＇s serotype wa predominated before 1980s,and the inaba＇s serotype was predominated in the recent years. Popular strains detected mainly from human bodies, and non-popular strains detected mainly from water source and other external environment. Conclusion Although the detection of Vibrio cholera reduced rapidly in recent years,cholera is still the major public health problem in this area due to the variation of Vibrioi cholera and appearance of O139 type.