甲亢平消丸对GD模型大鼠甲状腺激素的影响及对白细胞保护作用的实验研究

Study on affect of Jiakang Pingxiao Pill to thyroid hormone of GD mice and protcet of white blood cell

目的:观察甲亢平消丸对甲状腺功能亢进症(以下简称甲亢)模型大鼠甲状腺激素及对白细胞保护作用的影响。方法:甲状腺片复制甲亢动物模型,并以对体重、TT3、TT4、FT3、FT4、TSH的变化及对血中白细胞计数的影响为指标进行观察及研究。结果:甲亢平消丸对甲状腺片成功复制甲亢大鼠模型有明显的治疗作用,具有改善大鼠一般情况及增加大鼠体重的作用,有一定的抑制甲状腺功能的作用,抵抗他巴唑在治疗甲亢大鼠时对外周血中白细胞计数的影响。结论:甲亢平消丸可改善GD模型大鼠甲状腺激素水平并对白细胞有一定的保护作用,尤以中剂量中药合他巴唑组作用最为明显。

Objective：To observe affect of Jiakang Pingxiao pill to thyroid hormone of GD mice and protcet of white blood cell. Method： making animal model by thyroid tablet, weight TT3 ,TT4 , FT3, FT4 ,TSH and white blood cell were studied. Resuh：Jiakang Pingxiao pill can cure the hyperthyreosis obviously , increase weight rapidly, restraint the function of thyroid, counteract the affect to white blood cell. Conclusion：Jiakang Pingxiao pill can improve thyroid hormone of GD mice and protect white blood cell, especially to mid-dosage of tapazol.