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胸苷酸合成酶抑制剂的研究进展 被引量:2

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出处 《中国药房》 CAS CSCD 北大核心 2009年第31期2469-2470,共2页 China Pharmacy
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参考文献11

  • 1王伟,曹胜利,郭燕文,王先波.胸苷酸合酶抑制剂研究进展[J].中国新药杂志,2005,14(6):693-696. 被引量:5
  • 2尤启东.药物化学[M].第5版.北京:人民卫生出版社,2003:219-222.
  • 3Gangiee A, Li W, Yang J, et al. Design, synthesis, and biological evaluation of classical and nonclassical 2 - amino - 4 - oxo - 5 - substituted- 6 - methylpyrrolo [ 3,2- d] pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors [ J ] . J Meal Chem , 2008, 51(1) : 68.
  • 4张庆文.新一代抗叶酸类抗肿瘤药物[J].国外医药(合成药.生化药.制剂分册),1996,17(5):266-272. 被引量:5
  • 5Calvert H, Bunn PAl. Future directions in the development of pemetrexed[J ]. Semin Oncol, 2002,29(2 Suppl 5) : 54.
  • 6李世拥,于波,安萍,梁振家,苑树俊.胸苷酸合成酶基因表达与结肠直肠癌复发的关系及其临床意义[J].中华外科杂志,2000,38(10):781-783. 被引量:7
  • 7Jackman AL, Melin CJ, Kimbell R, et al . A rationale for the clinical development of the thymdylate synthase inhibitor ZD9331 in ovarian and other solid tumours[J ]. Biochim Biophys Acta, 2002,1 587(7) : 215.
  • 8Rader JS, Clarke - Pearson D, Morre M, et al. A phase II study to determine the efficacy and tolerability of intravenous ZD9331 in heavily pretreated patients with ovarian cancer [ J ] . Gynecol Oncol, 2003,91 ( 11 ) : 318.
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二级参考文献15

  • 1张庆文.新一代抗叶酸类抗肿瘤药物[J].国外医药(合成药.生化药.制剂分册),1996,17(5):266-272. 被引量:5
  • 2Smith D, Gallapher N. A phase Ⅱ/Ⅲ study comparing intravenous ZD9331 with gemcitabine in patients with pancreatic cancer[J]. Eur J Cancer, 2003,39(7) :1377 - 1383.
  • 3Mauritz R, Peters GJ, Priest DG. Et al. Multiple mechanisms of resistence to methotrexate and novel antifolates in human CCRFCEM leukemia cells and their implications for folate homeostasis[J]. Biochem Pharmacol,2002,63(2) :105 - 115.
  • 4Sternberg CN, Vogelzang NJ. Gemcitabine, paclitaxd, pemetrexed and other newer agents inurothelial and kidney cancers[J]. Hematol Oncol,2003,46(2) :105 - 115.
  • 5Dischof M, Huber P, Stoffregen C, et al. Radiosensitization by pemetrexed of human colon carcinoma cells in different cell cycle phases[J]. Int J Radiat Oncol Biol Phys,2003, 57 (1) :289 -292.
  • 6Kim SH, Brown SL, Kim JH. The potentiation of radiation response in human colon carcinoma cells in vitro and murine lymphoma in vitro by AG3379 (Thymitaq), a novel thymidylate synthase inhibitort [ J ]. Int J Radia Oncol Biol Phys, 1998, 42(4) :789 - 793.
  • 7Costi MP, Tondi D, Rinaldi M. Structure-based studies on species-specific inhibition of thymidylate synthase[J ]. Biochim Biophys Acta, 2002,1587 (2): 206 - 214.
  • 8尤启东.抗代谢药物[A]..药物化学[M]:第5版[C].北京:人民卫生出版社,2003.219-222.
  • 9Touroutoglou N,Pazdur R,Thymidylate Synthase inhibitors[J].Clin Cancer Res, 1996,2 (5): 227 - 243.
  • 10Hughes RL, Jackman AL, Oldfield J. Quinazoline antifolate thymidylate synthase inhibitors: Alkyl, substituted Alkly, and Aryl substituents in the C2 position[J]. J Med Chem, 1999,33(11): 3060 - 3067.

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