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心肌肌钙蛋白I、超敏C反应蛋白和尿酸联合检测在急性心肌梗死诊断中的意义 被引量:6

Diagnostic volue of the combined dection of cTnⅠ、hs-CRP and UA in patients with acute myocardial infarction
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摘要 目的 通过观察急性心肌梗塞(AMI)患者心肌肌钙蛋白Ⅰ(cWnⅠ、超敏C-反应蛋白(hs-CRP)和尿酸(UA)含量变化的测定,探讨阻止AMI的发生发展,达到抢救生命的临床意义。方法分别监测76例AMI患者cTnⅠ、hs—CRP,UA水平。结果单纯AMI患者cTnⅠ、hs—CRP,UA明显高于正常对照组(P〈0.01),其中合并二型糖尿病者(T2DM)hs-CRP,UA高于单纯AMI组(P〈0.05),而合并T2DM者心肌肌钙蛋白Ⅰ与单纯AMI组比较无显著性差异(P〉0.05)。结论cTnⅠ、uA和hs-CRP与AMI的发生发展密切相关,因此,cTnⅠ、hs-CRP和UA联合检测,有助于对AMI的早期诊断和预后评估。 Objective To explore the diagnositc value of combined dection of cardiac troponin Ⅰ (cTnⅠ) ,high sensitivity C-reactive protein(hs-CRP) and Uric acid (UA)in the patients with AMI. Methods The eTnI,hs-CRP and UA were measured in 128 patients with AMI. Results The levels of cTnⅠ,hs-CRP and UA in simple AMI patients were higher than normal controls signifieantly( P 〈 0. 01 ). The levels of hs-CRP and UA in the AMI patients with type 2 diabetes mellitus(T2DM) were higher than the simple AMI patients( P 〈 0.01 ). There were no statistical differences in the cTnⅠ between the AMI patients with T2DM and the simple AMI patlents(P 〉 0. 05). Conclusion The cTnⅠ. hs-CRP and UA are correlated with generation and development of AMI, therefore, the combined deetion of eTnI.hs-CRP and UA contributes to the early diagosis and prognosis evaluation of AMI.
出处 《中国临床实用医学》 2009年第11期19-21,共3页 China Clinical Practical Medicine
关键词 急性心肌梗死 心肌肌钙蛋白Ⅰ 超敏C反应蛋白 尿酸 Acute Myocardial Infaretion Cardiac treponin Ⅰ High sensitivity C-reactive protein Uric acid
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