心肌肌钙蛋白I、超敏C反应蛋白和尿酸联合检测在急性心肌梗死诊断中的意义

Diagnostic volue of the combined dection of cTnⅠ、hs-CRP and UA in patients with acute myocardial infarction

目的 通过观察急性心肌梗塞（AMI）患者心肌肌钙蛋白Ⅰ（cWnⅠ、超敏C-反应蛋白（hs-CRP）和尿酸（UA）含量变化的测定，探讨阻止AMI的发生发展，达到抢救生命的临床意义。方法分别监测76例AMI患者cTnⅠ、hs—CRP，UA水平。结果单纯AMI患者cTnⅠ、hs—CRP，UA明显高于正常对照组（P〈0．01），其中合并二型糖尿病者（T2DM）hs-CRP，UA高于单纯AMI组（P〈0．05），而合并T2DM者心肌肌钙蛋白Ⅰ与单纯AMI组比较无显著性差异（P〉0．05）。结论cTnⅠ、uA和hs-CRP与AMI的发生发展密切相关，因此，cTnⅠ、hs-CRP和UA联合检测，有助于对AMI的早期诊断和预后评估。

Objective To explore the diagnositc value of combined dection of cardiac troponin Ⅰ （cTnⅠ） ,high sensitivity C-reactive protein（hs-CRP） and Uric acid （UA）in the patients with AMI. Methods The eTnI,hs-CRP and UA were measured in 128 patients with AMI. Results The levels of cTnⅠ,hs-CRP and UA in simple AMI patients were higher than normal controls signifieantly（ P 〈 0. 01 ）. The levels of hs-CRP and UA in the AMI patients with type 2 diabetes mellitus（T2DM） were higher than the simple AMI patients（ P 〈 0.01 ）. There were no statistical differences in the cTnⅠ between the AMI patients with T2DM and the simple AMI patlents（P 〉 0. 05）. Conclusion The cTnⅠ. hs-CRP and UA are correlated with generation and development of AMI, therefore, the combined deetion of eTnI.hs-CRP and UA contributes to the early diagosis and prognosis evaluation of AMI.