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色氨酸羟化酶基因和抑郁症 被引量：1

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作者 曹岚 洪武 方贻儒
机构地区 上海交通大学医学院附属精神卫生中心
出处 《上海精神医学》 2009年第5期306-307,314,共3页 Shanghai Archives of Psychiatry
基金 上海市卫生局青年科研项目(2006Y018) 国家高技术研究发展计划(2006AA02Z403) "十五"国家科技攻关计划(2004BA72021-02) 上海市登山行动计划(064119533)
关键词 抑郁症 酶基因 色氨酸 羟化 流行病学资料 5-羟色胺 临床药理学 致残率高
分类号 R749.4 [医药卫生—神经病学与精神病学] R730.5 [医药卫生—肿瘤]
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参考文献24

  • 1Nielsen DA, Virkkunen M, Lappalainen J, et al. A tryptophan hydroxylase gene marker for suicidality and alcoholism. Arch Gen Psychiat, 1998,55 (7) ,593 - 602.
  • 2Mann JJ, Malone KM, Nielsen DA, et al. Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior in depressed patients. Am J Psychiat, 1997, 154 ( 10 ) : 1451 - 1453.
  • 3Abbar M, Courtet P, Amadeo S, et al. Suicidal behaviors and the tryptophan hydroxylase gene. Arch Gen Psychiat, 1995, 52 ( 10 ) : 846 - 849.
  • 4Kunugi H, Ishida S, Kato T, et al. No evidence for an association of polymorphisms of the tryptophan hydroxylase gene with affective disorders or attempted suicide among Japanese patients. Am J Psychiat, 1999,156(5) : 774 -776.
  • 5Tsai Shih - Jen, Hong Chen - Jee, Wang Ying - Chieh. Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors. Neuroreport, 1999, 10(18):3773-3775.
  • 6Abbar M, Courtet P, Bellivier F, et al. Suicide attempts and the tryptophan hydroxylase gene. Mol Psychiatr, 2001,6(3 ) :268 - 273.
  • 7Ham B J, Lee MS, Lee H J, et al. No association between the tryptophan hydroxylase gene polymorphism and major depressive disorders and antidepressant response in a Korean population. Psychiatric Genes, 2005,15(4) :299 -301.
  • 8Kunugi H, Ishida S, KatoT, et al. No evidence for an association of polymorphisms of the tryptophan hydroxylase gene with affective disorders or attempted suicide among Japanese patients. Am J Psychiat, 1999,156 (5) :774 - 776.
  • 9施梅,刘薇,潘尚哈,毛晶,陈力.TPH基因A218C多态性与单相抑郁症及其症状表型的关联分析[J].中国神经精神疾病杂志,2006,32(4):332-335. 被引量：11
  • 10Du L, Bakish D, Pavel D, et al. Tryptophan hydroxylase gene 218A/C polymorphism is associated with somatic anxiety in major depressive disorder. J Affect Disord, 2001,65( 1 ) :37 -44.

二级参考文献26

  • 1张玉琦,李克,李桂林,王爱荣,刘朝军,刘庆海,成义仁.抑郁症自杀行为遗传流行病学对照研究[J].中国神经精神疾病杂志,2005,31(1):40-42. 被引量：12
  • 2Craig SP,Boularand S,Darmon MC,et al.Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3-p14 by in situ hybridization.Cytogenet Cell Genet,1991,56(3 -4):157.
  • 3Nielsen DA,Goldman D,Virkkunen M,et al.Suicidality and 5 -hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism.Arch Gen Psychiatry,1994,51 (1):34.
  • 4Bellivier F,Leboyer M,Courtet P,et al.Association between the tryptophan hydroxylase gene and manic-depressive.Arch Gen Psychiatry,1998,55 (1):33.
  • 5Souery D,Gestel SV,Massat I,et al.Tryptophan hydroxylase polymorphism and suicidality in unipolar and bipolar affective disorders:a multicenter association study.Biol Psychiatry,2001,49(5):405.
  • 6Tsai SJ,Hong CJ,Wang YC.Tryptophan hydroxylase gene polymorphism (A218 C) and suicidal behaviors.Neuroreport,1999,10 (18):3773.
  • 7Tan EC,Chan AO,Tan CH,et al.Case-control and linkage disequilibrium studies of the tryptophan hydroxylase gene polymorphisms and major depressive disorder.Psychiatr Genet,2003,13 (3):151.
  • 8Rietschel M,Schorr A,Albus M,et al.Association study of the tryptophan hydroxylase gene and bipolar affective disorder using family-based internal controls.Am J Med Genet,2000,96(3):310.
  • 9Kunugi H,Ishida S,Kato T,et al.No evidence for an association of polymorphisms of the tryptophan hydroxylase gene with affective disorders or attempted suicide among Japanese patients.Am J Psychiatry,1999,156(5):774.
  • 10Seretti A,Cusin C,Lattuada E,et al.Serotonin transporter gene (5-HTTLPR) is not associated with depressive symptomatology in mood disorders.Mol Psychiatry,1999,4 (3):280.

共引文献23

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二级引证文献3

上海精神医学
2009年 第5期

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