小肝癌及其癌周肝组织内HBcAg的分布

DISTRIBUTION OF HBcAg IN TISSUES OF 65 SMALL LIVER CANCER CASES

为了进一步明确HBV感染与肝癌发生的相关性,我们采用灵敏、可靠的PAP免疫组化方法,对65例小肝癌及其癌周肝组织进行了乙型肝炎核心抗原(HBcAg)标记,现将结果报告如下。

HBcAg in tissues of 65 cases of small liver cacinoma and 19 cases of non-h-epatoma were marked by PAP immunohistochemical method. The positive rates of HBcAg in the tissues of liver cancer were9.2%,in the surrounding hepatic tissues were47.69%,and tissues of non-hepatoma were10.53%. The phenotype patterns of HBcAg could be diveded into nucleus type, cytoplasmic type and mixed type. The positive rates were 38.71%,19.35%and 41.94%respectively in the all positive specimens of HBcAg. The positive rates of HBcAg were markedly discrepant with or without cirrhosis and hepatocellular Extentocellular of hepatece. Ilular damage varied with different phenotype patterns