肿瘤合并静脉血栓栓塞相关影响因素

The impat factors of venous thromboembolism in carcinoma

肿瘤合并静脉血栓栓塞（VTE）是导致患者生活质量下降及死亡的主要原因之一，危险因素包括病理类型及临床分期、手术切除、肿瘤转移、联合使用有针对性的化疗药物和新的分子靶向药物如抗血管内皮细胞生长因子（VEGF）的药物。目前其机制研究主要集中于有活性的微粒相关组织因子。因此深入研究肿瘤合并VTE的危险因素，对指导临床防治具有重要价值。

Carcinoma complicating venous thromboembolism（ VTE ）is very important agent to lead to descent of patient＇s life quality. Risk factors of venous thromboembolism in carcinoma patients are adenocarcinoma, metastatic disease,pneumonectomy and anticancer therapy including chemotherapy and anti-vascular endothelial growth facor targeted drugs. Nowadays ,most of researches focus on active tissue factor（TF） related to microparticles. It is significant to have a deep investigation on risk factor of venous thromboembolism in carcinoma for clinic prevention and treatment.