摘要
本文设计并实现了基于质谱的非标记定量软件QuantWiz,通过改变肽段定量的顺序,提高了定量软件的时间局部性和质谱数据缓存的命中次数。分析了QuantWiz的多种数据并行策略,设计并实现了按保留时间划分的并行定量软件P-QuantWiz。通过实验验证P-QuantWiz具有良好的并行效率,当进程数为32时,并行效率为63%。
A new label-free quantification software based on mass spectrometry, named QuantWiz, is designed and implemented in this paper. By changing the order of peptide quantification, the time locality and mass spectrometry data cache hits of QuantWiz are improved. The data parallel strategies are also analyzed, and the parallel quantification software called P-QuantWiz based on retention time partitioning is designed and implemented. A lot of experiments show that the parallelism efficiency is very high, whenever the process number is 32, the parallelism efficiency is 63%.
出处
《计算机工程与科学》
CSCD
北大核心
2009年第11期124-127,共4页
Computer Engineering & Science
基金
中科院知识创新工程重大项目(KGCX1-YW-13)
关键词
质谱
非标记定量
色谱峰
保留时间
并行化
mass spectrometry
label-free quantification
chromatographic peaks
retention time
parallelization
