摘要
目的介绍肝癌血管生成的分子机理及抗血管生成在肝癌发展与治疗中的作用与意义。方法复习相关文献资料并作综述。结果肝癌血管生成在肝癌的发生与发展中具有重要意义,抗血管生成能有效地阻碍肝癌的发展和转移,可为临床肝癌治疗提供新的途径。结论了解肝癌血管生成的分子机理及应用抗血管生成治疗对肝癌的防治将有积极的意义。
Objective To introduce the possible effects and significances of angiogenesis and antiangiogenic in the development and treatment of hepatocellular carcinoma（HCC）.Methods Recently relevant literatures were reviewed.Results Angiogenesis played a significant role in the development and therapy of HCC,and the development and metastasis of HCC could be effectively suppressed by antiangiogenic therapy.This might provide a new approach for the treatment of HCC.Conclusion Comprehending the molecular mechanism of angiogenesis and applying antiangiogenic therapy will contribute a lot for the prevention and treatment of HCC.
出处
《中国普外基础与临床杂志》
CAS
2009年第10期861-865,共5页
Chinese Journal of Bases and Clinics In General Surgery
基金
广东省科技厅科技计划项目资助(项目编号:E00200603
2005B30301018)~~
关键词
肝细胞肝癌
血管生成
抗血管生成治疗
转移
Hepatocellular carcinoma
Angiogenesis
Antiangiogenic therapy
Metastasis
