药疹的遗传学发病机制研究进展
摘要
药疹的原因复杂,与药物的药理作用,毒性反应,过敏反应和人的特异体质等因素密切相关。药疹的发生具有家族聚集性和HLA基因易感性。药物代谢酶的基因变异容易导致药物代谢和解毒过程的失衡,另外,细胞因子和趋化因子受体表达水平的差异,在药疹的发生中也起到重要作用。
出处
《中国麻风皮肤病杂志》
2009年第10期760-762,共3页
China Journal of Leprosy and Skin Diseases
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