两种根面处理剂用于牙周翻瓣术的临床疗效

A comparative study of clinical effect of applying two kinds of root surface conditioner during flap surgery

目的:评价盐酸多西环素和EDTA两种根面处理剂对牙周翻瓣术后临床疗效。方法:选择牙周基础治疗4周后的慢性牙周炎病人30例,共90个翻瓣术区作为研究对象,每例病人选择口腔内3个病情相近的术区,分为盐酸多西环素处理组(DH组)、EDTA处理组、仅进行牙周翻瓣术的空白对照组(OFD组)。术前检查记录龈沟出血指数(sulcus bleeding index,SBI)、牙周袋探诊深度(pocket probing depth,PPD)、附着丧失(clinical atachment loss,CAL)。术中根面平整后,实验组分别以EDTA和盐酸多西环素涂擦根面,3 min后,生理盐水冲洗,缝合。空白对照组仅用生理盐水冲洗后缝合。术后3个月复查,检查记录龈沟出血指数(SBI)、牙周袋探诊深度(PPD)、附着丧失(CAL)。SPSS10.0软件包对相关数据统计学分析。结果:术后3个月,3组PPD、CAL、SBI均较术前明显减少(P<0.05),盐酸多西环素处理组、EDTA处理组与空白对照组相比,减少更为明显(P<0.05);盐酸多西环素处理组与EDTA处理组相比,PPD和CAL减少更为明显(P<0.05),而SBI在3组间均无显著性差异(P>0.05)。结论:两种根面处理剂均能有效提高翻瓣术治疗慢性牙周炎的临床效果,以盐酸多西环素效果更佳。

AIM： To compare the clinical results of applying two root surface conditioner （ doxycycline hydrochloride and EDTA） after flap surgery, and to evaluate the effect of two root surface conditioner after periodontal flap surgery. METHODS ：30 patients were choosen, who have chronic periodontitis 4 weeks after initial therapy, totally with 90 surgical flap areas as the research object. Each patient has at least 3 similar surgical areas, which were divided into 3 groups （DH group, EDTA group, OFD group） and checking to record SBI, PPD and CAL before surgery. The teeth suffered from periodontitis were treated by a periodontal scaling and root planing, then embrocated EDTA or doxycycline hydrochloride onto root surface, then rinsed with normal saline. The OFD group rinsed by normal saline only. All the flaps were sutured finally. After 3 months the wounds were rechecked to record SBI, PPD and CAL again. Finally, a statistical analysis of relative data were completed by a SPSS10.0 software package. RESULTS ： Patients of all three groups have obviously decreased in PPD, CAL, SBI, but the reduction of DH group and EDTA group were more notable than the OFD group, with significant difference （P 〈 0.05）. In comparison to the DH group and EDTA group, DH group had a larger decrease than EDTA group in PPD and CAL, which having a significant difference （P 〈0. 01 ）, but without significant difference in SBI （ P 〉 0.05 ）. CONCLUSION： Both of two root surface conditioner could improve the effect of treatment in chronic periodontitis by flap surgery. But the DH have a better healing effect than the EDTA.