中国与加拿大合作开展健康与衰老研究的情况介绍

Quantification of health and ageing in Canada and China： a Canada-China joint health research initiative project

2009年初，由中国国家自然科学基金委员会（NSFC）与加拿大国家卫生研究院（CIHR）资助的科研课题“中国和加拿大老年人健康状况改变的定量分析——衰老的数学模型评估”正式宣布立项。这是中加两国的老年医学工作者首次在两国国家级研究机构的共同资助下，合作开展有关衰老与寿命的基础与临床研究。中国与加拿大政府于2005年末开展健康研究合作计划，重点资助包括衰老在内的7个方面的医学研究，旨在支持和推动中国和加拿大在卫生领域的交流与合作，

Improving health care in later life is crucial, especially under the impact of world population ageing. It provides challenges and opportunities for health and ageing research, and global co-operations and joint commitments among different countries are needed. Supported by the Canada-China Joint Health Research Initiative Program, the Canada China Study in Ageing and Longevity is the first research of the kind to compare the process of ageing and health changes between Canadian and Chinese. The collaboration sets up a data and knowledge sharing agreement between the participate partners. The initial proposal was for the ＂ Quantification of health status changes in China and in Canada： an evaluation of a stochastic model of health transition＂. As the project evolves, however, the focus is expanding to develop a quantative method to assess frailty in elderly Chinese people, corresponding to information collected in Canada in Comprehensive Geriatric Assessments （CGAs）. The Canadian team has established the Frailty Index and a stochastic ageing model, which despite mathematically simplicity, can capture characteristic health statue changes. The model will be applied to study Chinese datasets and parameters will be compared between different countries. In additional, a new version of the Frailty Index, based on a CGA （the FI-CGA） will be developed, tested and modeled. Through various research activities, the collaborative research will allow quantification not only of the impact of ageing, but also of the impact of a feasible intervention on improving public health in different social settings.