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多环芳烃的致癌性及其机制研究进展 被引量:41

Carcinogenicity of polycyclic aromatic hydrocarbons and research progress of the mechanisms
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摘要 本文综合近年来国内外有关多环芳烃(PAHs)致癌性的研究资料,着重从细胞色素P450、环氧化物水解酶、谷胱甘肽硫转移酶、PAH-DNA加合物等方面,概述了多环芳烃的致癌性及其机制,为PAHs的致癌机制研究提供一定的思路。 This paper reviews investigations about the carcinogenicity of polycyclic aromatic hydrocarbons(PAHs) and mainly expounds cytochrome P450,epoxide hydrolase,glutathione S-transferase,PAH-DNA adducts in an attempt to provide ideas for a deep research in the carcinogenic mechanisms of PAHs.
作者 贾鸿宁 戴红
出处 《大连医科大学学报》 CAS 2009年第5期604-607,620,共5页 Journal of Dalian Medical University
关键词 多环芳烃 致癌性 机制 polycyclic aromatic hydrocarbon(PAHs) genotoxicity mechanism
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