前庭代偿:研究中枢神经系统可塑性的一个理想模型

Vestibular Compensation:A Privileged Model for the Study on Plasticity of Central Nervous System

前庭代偿是一个研究神经系统损伤后机能修复和替代的理想模型。这个模型在中枢神经系统可塑性和机能恢复的研究中具有普遍意义。本文综述了有关前庭代偿的电生理学、生物化学和分子神经生物学的研究现状。

Vestibular compensation is now considered as a privileged model for the study of the underlying mechanisms of restitution and substitution of functions after nervous system lesions. This model is ubiquitously suited for the research of plasticity of central nervous system and recuperation of functions. This review focuses on the latest progress of the research on vestibular compensation in the aspects of electrophysiology, biochemistry and molecular neurobiology as well as the expression of growthassociated protein(GAP43), and the pharmacological effects of extract of Ginkgo biloba(EGb 761) during the course of vestibular compensation are specially discussed.