口服小分子靶向抗肿瘤药物的不良反应及防治措施

Prevention and treatments for adverse drug reactions of oral small molecular targeting drugs

目前已有多个口服小分子靶向抗肿瘤药物在我国上市,文中对近年相关文献进行归纳、分析,从皮肤系统、消化系统、循环系统、血液系统等方面综述此类药物的不良反应和防治措施,为临床医生安全合理用药及临床药师进行药学服务提供参考。

A number of oral small molecular targeting drugs have been already approved by State Food and Drug Administration of China. This review summarized and analyzed the prevention and treatments of adverse drug reactions for this kind of agents, including those in dermal, digestive, circulatory and hematological systems. The goal is to supply references for more rational use, and for clinical pharmacists to pharmaceutical care.